2012-04-07 (updated 2016-04-25)
The proper title shows the "c" is shown in superscript, meaning 0x10 to the power of c (in hexadecimal). Officially pronounced ten to the see. Or 16 to the power of 12 in decimal. Or fully calculated as 281,474,976,710,656 (the number of years added to 1998 by the computer bug).

A notable feature of this game is that all the spacecraft will have a fully emulated computer system with an accurately emulated late 80s CPU. In addition to this contributing to gameplay features, players will be able to pass the time (space travel will take a some time) by playing emulated 80s games.

2012-08-09
Notch has since given up on the use of hard scifi for the game, so it'll be just regular scifi.
Quoted from game features:
Hard science fiction. Update: GAH, NO! I'm focusing on fun gameplay instead. I still want to get corrected on glaring scientific errors, though.



source: 0x10c.com/