| title | developer | year | platform | | pop. |
|---|
| UFO: Afterlight | ALTAR Games | 2007 | Windows | strategy role-play Science Fiction | image | subject | label | |
| UFO: Extraterrestrials | Chaos Concept | 2007 | Windows | strategy turn-based Science Fiction | image | subject | label | |
| Ultima IX: Ascension | Origin | 1999 | Windows | action/reflex role-play Fantasy | image | subject | label | |
| Unclaimed World | Refactored Games | 2016 | Windows | simulation | image | | label | |
| Unreal | Epic Games | 2002 | Linux | shooter Science Fiction | | subject | label | |
| Unreal | Epic MegaGames;Digital Extremes | 1998 | Windows | shooter Science Fiction | image | | label | |
| Unreal | Westlake Interactive;Epic MegaGames;Digital Extremes | 1999 | Mac OS Classic | shooter Science Fiction | | | label | |
| Unreal II – The Awakening | Legend Entertainment | 2003 | Windows | shooter Science Fiction | image | | label | |
| Unreal Mission Pack: Return to Na Pali | Legend Entertainment | 1999 | Linux | shooter Science Fiction | image | | label | |
| Unreal Mission Pack: Return to Na Pali | Legend Entertainment | 1999 | Windows | shooter Science Fiction | | | label | |
| Unreal: Return to Na Pali | Legend Entertainment | 1999 | Windows | shooter adventure Science Fiction | image | | label | |
| Unstoppable Gorg | Futuremark Games Studio | 2012 | Windows | strategy Science Fiction | image | subject | label | |
| Unstoppable Gorg | Futuremark Games Studio | 2012 | X360 | strategy Science Fiction | image | | label | |
| Unstoppable Gorg | Futuremark Games Studio | 2012 | iOS | strategy Science Fiction | | | label | |
| Unstoppable Gorg | Futuremark Games Studio | 2012 | Mac OS X | strategy Science Fiction | image | | label | |
| Vector 36 | Red River Studio | 2017 | Linux | racing/driving Science Fiction | | | label | |
| Vector 36 | Red River Studio | 2017 | Mac OS X | racing/driving Science Fiction | | | label | |
| Vector 36 | Red River Studio | 2017 | Windows | racing/driving Science Fiction | | | label | |
| Venus Senki | Human | 1989 | NES | action/reflex strategy turn-based Manga | image | | label | |
