| title | developer | year | platform | | pop. |
|---|
| AI War: Fleet Command | Arcen Games | 2009 | Windows | strategy Science Fiction | image | | label | |
| AI War: Fleet Command | Arcen Games | 2014 | Linux | strategy Science Fiction | | | label | |
| Ascendancy | The Logic Factory | 1995 | MS-DOS | strategy turn-based Science Fiction | image | | label | |
| Ascendancy | The Logic Factory | 2011 | iOS | strategy turn-based Science Fiction | | | label | |
| Black Market | Big Block Games | 2011 | Internet Only | role-play | image | | label | |
| Conquest: Frontier Wars | Fever Pitch Studios;Digital Anvil | 2001 | Windows | manag./econ. strategy Science Fiction | image | subject | label | |
| DarkStar One | Ascaron Entertainment | 2006 | Windows | shooter adventure Science Fiction | image | subject | label | |
| Darkstar One: Broken Alliance | Ascaron Entertainment | 2010 | X360 | shooter Science Fiction | image | | label | |
| Endless Space | Amplitude Studios | 2012 | Windows | strategy Science Fiction | image | subject | label | |
| EVE Online | CCP Games | 2003 | Windows | simulation role-play Science Fiction | image | | label | |
| Freelancer | Digital Anvil | 2003 | Windows | action/reflex shooter flight Science Fiction | image | subject | label | |
| Freelancer | author | 2016 | Linux | action/reflex shooter flight Science Fiction | | | label | |
| Mass Effect | BioWare | 2007 | X360 | action/reflex role-play Science Fiction | image | | label | |
| Mass Effect | BioWare;Demiurge Studios | 2008 | Windows | action/reflex role-play Science Fiction | image | subject | label | |
| Mass Effect 2 | BioWare Edmonton;EA Montreal | 2010 | X360 | action/reflex role-play Science Fiction | image | subject | label | |
| Mass Effect 2 | BioWare;EA Montreal | 2010 | Windows | action/reflex shooter role-play Science Fiction | image | subject | label | |
| Mass Effect 2 | BioWare Edmonton;EA Montreal | 2011 | PS3 | action/reflex role-play Science Fiction | image | | label | |
| Master of Orion | MicroProse | 1990 | Mac OS Classic | manag./econ. strategy turn-based Science Fiction | image | | label | |
| Master of Orion III | Quicksilver Software | 2003 | Windows | manag./econ. strategy turn-based Science Fiction | image | subject | label | |
| Master of Orion III | Quicksilver Software;MacSoft | 2003 | Mac OS Classic | manag./econ. strategy turn-based Science Fiction | image | | label | |
| Master of Orion III | Quicksilver Software;MacSoft | 2003 | Mac OS X | manag./econ. strategy turn-based Science Fiction | | | label | |
| Orion Trail | Schell Games | 2015 | Linux | simulation adventure Humorous | | | label | |
| Orion Trail | Schell Games | 2015 | Windows | simulation Humorous | image | | label | |
| Rebel Galaxy | Double Damage Games | 2015 | Windows | action/reflex Science Fiction | image | | label | |
| Remember Tomorrow | SoftWarWare | 1998 | MS-DOS | strategy Science Fiction | | | label | |
| Sins of a Solar Empire | Ironclad Games | 2008 | Windows | manag./econ. strategy Science Fiction | image | subject | label | |
| Sins of a Solar Empire: Entrenchment | Ironclad Games | 2009 | Windows | simulation manag./econ. strategy Science Fiction | image | | label | |
| Space Exploration: Serpens Sector | Metal Beetle | ? | Linux | role-play Science Fiction | | | label | |
| Space Pirates and Zombies | MinMax Games | 2011 | Windows | action/reflex Science Fiction | image | subject | label | |
| Space Pirates and Zombies | MinMax Games | 2012 | Linux | action/reflex Science Fiction | | | label | |
| Space Pirates and Zombies | MinMax Games | 2012 | Mac OS X | action/reflex Science Fiction | | | label | |
| Space Pirates and Zombies 2 | MinMax Games | 2017 | Linux | action/reflex Science Fiction | | | label | |
| Star Control | Toys for Bob | 1990 | MS-DOS | action/reflex strategy Science Fiction | image | | label | |
| Star Control | Toys for Bob | 1990 | Amiga | action/reflex strategy Science Fiction | image | | label | |
| Star Control | Toys for Bob | 2012 | Mac OS X | action/reflex strategy Science Fiction | | | label | |
| Star Trek: Conquest | 4J studios | 2007 | Wii | action/reflex strategy Science Fiction | image | subject | label | |
| Star Trek: Conquest | 4J studios | 2007 | PS2 | action/reflex strategy Science Fiction | image | | label | |
| Starscape | Moonpod | 2003 | Windows | shooter adventure turn-based Science Fiction | image | subject | label | |
| Strange Adventures in Infinite Space | Digital Eel | 2002 | Windows | strategy adventure Science Fiction | | | label | |
| Strange Adventures in Infinite Space | Digital Eel | 2002 | Mac OS X | strategy adventure Science Fiction | | | label | |
| Strange Adventures in Infinite Space | Digital Eel | ? | Palm | strategy adventure Science Fiction | | | label | |
| Strange Adventures in Infinite Space | Digital Eel | ? | WinCE | strategy adventure Science Fiction | | | label | |
| Strange Adventures in Infinite Space | Digital Eel | ? | Linux | strategy adventure Science Fiction | | | label | |
| The Orion Trail | Crow Cousins | 2021 | Apple II E | action/reflex simulation manag./econ. adventure Science Fiction | | | label | |
| X: Beyond the Frontier | Egosoft | 1999 | Windows | action/reflex simulation flight manag./econ. Science Fiction | image | subject | label | |
| X²: The Threat | Egosoft | 2003 | Windows | action/reflex simulation flight manag./econ. adventure Science Fiction | image | subject | label | |
| X²: The Threat | Egosoft;Linux Game Publishing | 2006 | Linux | action/reflex simulation flight manag./econ. Science Fiction | image | subject | label | |
| X²: The Threat | Egosoft | 2003 | Windows | action/reflex simulation flight manag./econ. Science Fiction | | | label | |
| X³: Farnham's Legacy | EGOSOFT | 2021 | Linux | action/reflex simulation flight manag./econ. adventure Science Fiction | | | label | |
| X³: Reunion | Egosoft | ? | Mac OS X | action/reflex simulation flight manag./econ. adventure Science Fiction | | | label | |
| X³: Reunion | Egosoft;Linux Game Publishing;Streamline Studios | 2008 | Linux | action/reflex simulation flight manag./econ. adventure Science Fiction | image | subject | label | |
| X³: Reunion | Egosoft | 2005 | Windows | action/reflex simulation flight manag./econ. adventure Science Fiction | image | | label | |
| X4: Foundations | Egosoft | 2019 | Linux | action/reflex simulation flight manag./econ. adventure Science Fiction | | | label | |
