| title | developer | year | game type | | pop. |
|---|
| A-Rank Thunder Tanjouhen | Riot | 1993 | Mega-CD | role-play Manga | image | | | |
| After Armageddon Gaiden | Micro Design;Brain Grey | 1994 | Mega-CD | role-play | image | | label | |
| After Burner III | CRI | 1992 | Mega-CD | shooter flight | image | subject | label | |
| Aisle Lord | Wolf Team | 1992 | Mega-CD | role-play Fantasy | image | | label | |
| Alshark | Popcorn Soft | 1993 | Mega-CD | simulation Manga | image | | | |
| Annet Futatabi | Wolf Team | 1993 | Mega-CD | beat 'em up Manga | image | | label | |
| Aoki Ookami to Shiroki Mejika: Genchou Hishi | ? | 1993 | Mega-CD | | image | | | |
| Arcus I.II.III | Wolf Team | 1993 | Mega-CD | role-play Manga | image | | label | |
| AX-101 | Micronet;Absolute Entertainment | 1994 | Mega-CD | shooter Science Fiction | image | subject | label | |
| Baku Den: The Unbalanced Zone | Sony Computer Entertainment | 1994 | Mega-CD | | image | | | |
| Bari-Arm | Human | 1994 | Mega-CD | shooter Manga | image | | label | |
| Batman Returns | ACME Interactive | 1993 | Mega-CD | beat 'em up racing/driving | image | | label | |
| Battle Frenzy | Domark | 1995 | Mega-CD | shooter | image | subject | label | |
| Battlecorps | Core Design | 1994 | Mega-CD | shooter | image | | label | |
| BC Racers | Core Design | 1995 | Mega-CD | racing/driving | image | | label | |
| Bill Walsh College Football | High Score Productions | 1993 | Mega-CD | sport | image | | label | |
| Black Hole Assault | Micronet | 1992 | Mega-CD | fighting Science Fiction | image | subject | label | |
| Bouncers | Sierra On-Line | 1994 | Mega-CD | action/reflex | image | | label | |
| Bram Stoker's Dracula | Psygnosis | 1992 | Mega-CD | beat 'em up | image | subject | label | |
| Brutal: Paws of Fury | GameTek | 1994 | Mega-CD | fighting | image | | label | |
| Bug Blasters: The Exterminators | Stargate Films | 2001 | Mega-CD | shooting gallery | image | | label | |
| Burai | Information Global Service | 1992 | Mega-CD | role-play Manga | image | | | |
| Burning Fists: Force Striker | Evermind Development | 2006 | Mega-CD | fighting | image | subject | | |
| Cadillacs and Dinosaurs: The Second Cataclysm | Rocket Science Games | 1994 | Mega-CD | Fantasy | image | | label | |
| Capcom no Quiz Tonosama no Yabou | CAPCOM | 1992 | Mega-CD | | | | | |
| Capcom Quiz Tono-sama no Ambition | Sims | 1992 | Mega-CD | trivia/quiz | image | | | |
| Captain Tsubasa | Tecmo | 1994 | Mega-CD | sport Manga | image | | label | |
| Championship Soccer 94 | Sensible Software | 1993 | Mega-CD | sport | image | | label | |
| Chuck Rock | Core Design | 1992 | Mega-CD | platformer | image | | label | |
| Chuck Rock II: Son of Chuck | Core Design | 1993 | Mega-CD | platformer | image | | label | |
| Citizen X | Digital Pictures | 2002 | Mega-CD | platformer | image | | label | |
| Cliffhanger | Sony | 1993 | Mega-CD | | image | | label | |
| Cobra Command | Wolf Team | 1992 | Mega-CD | shooting gallery | image | | label | |
| Corpse Killer | Digital Pictures | 1994 | Mega-CD | shooting gallery Horror | image | | label | |
| Cosmic Fantasy Stories | Nihon Telenet | 1992 | Mega-CD | role-play Manga | image | | label | |
| Crime Patrol | American Laser | 1994 | Mega-CD | shooting gallery | image | | label | |
| Cyborg 009 | Riot | 1993 | Mega-CD | platformer Manga | image | | label | |
| Daihoushinden | Flashback | 1995 | Mega-CD | role-play | image | | | |
| Dark Seed | Cyberdreams | 1993 | Mega-CD | adventure Horror | | | label | |
| Dark Wizard | Renovation | 1993 | Mega-CD | strategy Fantasy | image | | label | |
| Death Bringer: The Knight of Darkness | Nihon Telenet | 1992 | Mega-CD | role-play Manga | image | | | |
| Demolition Man | Alexandria Incorporated | 1995 | Mega-CD | platformer | image | | label | |
| Detonator Orgun | Hot-B;Darts | 1992 | Mega-CD | adventure Manga | image | | label | |
| Devastator | Wolf Team | 1993 | Mega-CD | shooter Manga | image | | | |
| Double Switch | Digital Pictures | 1993 | Mega-CD | adventure | image | | label | |
| Dracula Unleashed | Sega | 1993 | Mega-CD | adventure | image | | label | |
| Dragon's Lair | Readysoft | 1993 | Mega-CD | action/reflex Fantasy | image | subject | label | |
| Dune | Cryo Interactive Entertainment | 1993 | Mega-CD | strategy adventure Science Fiction | image | | label | |
| Dungeon Explorer | Westone | 1995 | Mega-CD | adventure Fantasy | image | subject | label | |
| Dungeon Master II: Skullkeep | FTL Games | 1994 | Mega-CD | role-play Fantasy | image | subject | label | |
| Dynamic Country Club Golf | Sega | 1993 | Mega-CD | sport | image | | label | |
| Earnest Evans | Wolf Team | 1991 | Mega-CD | beat 'em up | image | | label | |
| Earthworm Jim: Special Edition | Shiny Entertainment | 1995 | Mega-CD | platformer Humorous | image | subject | label | |
| Ecco the Dolphin | Novotrade | 1993 | Mega-CD | action/reflex adventure Science Fiction | image | | label | |
| Ecco: The Tides of Time | Novotrade | 1993 | Mega-CD | maze adventure Fantasy | image | | label | |
| ESPN Baseball Tonight | Park Place Productions | 1993 | Mega-CD | sport | image | | label | |
| ESPN National Hockey Night | Sony Imagesoft | 1994 | Mega-CD | sport | image | subject | label | |
| ESPN NBA Hangtime '95 | Sony | 1994 | Mega-CD | sport | image | | label | |
| ESPN Sunday Night NFL | Ringler Studios | 1993 | Mega-CD | sport | image | subject | label | |
| Eternal Champions: Challenge from the Dark Side | Sega | 1994 | Mega-CD | fighting | image | subject | label | |
| Eye of the Beholder | FCI;Pony Canyon | 1994 | Mega-CD | action/reflex role-play Fantasy | image | subject | label | |
| F1 Circus CD | Video System | 1994 | Mega-CD | racing/driving | image | | label | |
| Fahrenheit | Digital Pictures | 1995 | Mega-CD | action/reflex | image | | label | |
| Fatal Fury Special | Funcom | 1994 | Mega-CD | fighting | image | subject | label | |
| Fey Area | Wolf Team | 1992 | Mega-CD | role-play Manga | image | | label | |
| FIFA International Soccer | EA Sports | 1994 | Mega-CD | sport | image | subject | label | |
| Final Fight CD | Capcom;A-Wave | 1993 | Mega-CD | beat 'em up | image | | label | |
| Flashback: The Quest for Identity | Delphine Software | 1993 | Mega-CD | action/reflex platformer adventure Science Fiction | image | subject | label | |
| Flink | Psygnosis | 1994 | Mega-CD | platformer | image | | label | |
| Flying Nightmares | Domark | 1995 | Mega-CD | flight | image | subject | label | |
| Formula 1 World Championship: Beyond the Limit | FCI;Pony Canyon | 1994 | Mega-CD | racing/driving | image | | label | |
| Frog Feast | RasterSoft | 2007 | Mega-CD | action/reflex | image | | label | |
| Funky Horror Band | JVC | 1991 | Mega-CD | role-play | image | | | |
| Gambler Jikkyo-Cyushinha 2: Struggle in the Tokyo Mahjong Land | Game Arts | 1992 | Mega-CD | board game Manga | image | | label | |
| Gambler Jiko Chuushinha 2 - Gekitou Tokyo Mahjong Land Hen | Game Arts | 1992 | Mega-CD | board game Manga | image | | label | |
| Game no Kanzume Volume 1 | Sega | 1994 | Mega-CD | action/reflex platformer adventure puzzle | image | | | |
| Game no Kanzume Volume 2 | Sega | 1994 | Mega-CD | | image | | label | |
| Genghis Khan 2: Clan of the Grey Wolf | Koei | 1993 | Mega-CD | strategy | image | | label | |
| Ground Zero Texas | Digital Pictures | 1993 | Mega-CD | | image | | label | |
| Heart of the Alien: Out of this World part II | Delphine | 1994 | Mega-CD | platformer adventure Science Fiction | image | subject | label | |
| Heavy Nova | Micronet | 1991 | Mega-CD | fighting | image | | label | |
| Heimdall | Core Design | 1994 | Mega-CD | adventure Historical | image | | label | |
| Hook | Sony Imagesoft | 1992 | Mega-CD | platformer Fantasy | image | | label | |
| Illusion City | Micro Cabin | 1993 | Mega-CD | role-play Manga | image | | | |
| Iron Helix | Brian A. Rice | 1994 | Mega-CD | adventure Science Fiction | image | subject | label | |
| Ishii Hisaichi no Daisekai | Sega | 1994 | Mega-CD | board game | image | | label | |
| Jaguar XJ220 | Core Design | 1992 | Mega-CD | racing/driving | image | subject | label | |
| Jango World Cup | JVC | 1993 | Mega-CD | board game | image | | label | |
| Jeopardy | Absolute Entertainment | 1994 | Mega-CD | trivia/quiz | image | subject | label | |
| Joe Montana's NFL Football | Sega | 1993 | Mega-CD | sport | image | subject | label | |
| Johnny Mnemonic | ? | 1995 | Mega-CD | adventure | image | | label | |
| Jurassic Park | Sega | 1993 | Mega-CD | shooting gallery | image | | label | |
| Karate King | Megastar Games | ? | Mega-CD | beat 'em up platformer | | | label | |
| Keio Flying Squadron | Victor Entertainment | 1993 | Mega-CD | shooter | image | subject | label | |
| Kids on Site | Digital Pictures | 1994 | Mega-CD | | image | | label | |
| Lethal Enforcers | Konami | 1993 | Mega-CD | shooting gallery | image | | label | |
| Lethal Enforcers II: Gun Fighters | Konami | 1994 | Mega-CD | shooting gallery | image | | label | |
| Links: The Challenge of Golf | Access | 1994 | Mega-CD | sport | image | subject | label | |
| Loadstar: The Legend of Tully Bodine | Rocket Science Games | 1994 | Mega-CD | shooter | image | | label | |
| Lunar: Eternal Blue | Game Arts | 1994 | Mega-CD | role-play Fantasy | image | subject | label | |
| Lunar: The Silver Star | Game Arts | 1992 | Mega-CD | role-play Manga | image | subject | label | |
| Mad Dog II: The Lost Gold | American Laser Games | 1993 | Mega-CD | shooting gallery | image | subject | label | |
| Mad Dog McCree | American Laser Games | 1992 | Mega-CD | shooting gallery | image | subject | label | |
| Magical Girl Silky Lip | Telenet | 1992 | Mega-CD | adventure role-play Manga | image | | | |
| Make My Video: INXS | Digital Pictures | 1992 | Mega-CD | rhythm | image | | label | |
| Make My Video: Kris Kross | Digital Pictures | 1992 | Mega-CD | rhythm | image | | label | |
| Make My Video: Marky Mark and the Funky Bunch | Sony | 1992 | Mega-CD | rhythm | image | | label | |
| Marko's Magic Football | The Cartoon Mavericks | 1993 | Mega-CD | platformer | image | subject | label | |
| Mary Shelley's Frankenstein | Sony Imagesoft | 1993 | Mega-CD | adventure Horror | image | | label | |
| Mega Schwarzschild | Kogado Studio | 1993 | Mega-CD | | image | | | |
| MegaRace | Cryo Interactive | 1994 | Mega-CD | action/reflex racing/driving | image | | label | |
| Mickey Mania: The Timeless Adventures of Mickey Mouse | Traveller's Tales | 1994 | Mega-CD | platformer | image | | label | |
| Microcosm | Psygnosis | 1993 | Mega-CD | shooter Science Fiction | image | | label | |
| Midnight Raiders | Digital Pictures | 1994 | Mega-CD | shooting gallery | image | | label | |
| Might and Magic III: Isles of Terra | New World Computing;CRI | 1993 | Mega-CD | role-play Fantasy | image | | label | |
| Mighty Mighty Missile | Oldergames.com | 2004 | Mega-CD | puzzle | image | subject | | |
| Mighty Morphin Power Rangers | Sega | 1995 | Mega-CD | action/reflex | image | | label | |
| Mortal Kombat | Midway;Probe | 1993 | Mega-CD | fighting | image | subject | label | |
| My Paint: The Animated Paint Program | Bridgestone Multimedia | 1993 | Mega-CD | | image | subject | label | |
