| title | developer | year | platform | | pop. |
|---|
| E.T. The Extra-Terrestrial: Away from Home | Ubi Soft | 2002 | Windows | board game | | | label | |
| Echoes of the Fey Episode 0: The Immolation | Woodsy Studio | 2017 | Linux | adventure | | | label | |
| Edna | Black Raven | 1997 | MS-DOS | action/reflex adventure Fantasy | | | label | |
| Edna & Harvey: Harvey's New Eyes | Daedalic Entertainment | TBA | Linux | adventure | | | label | |
| Edna & Harvey: Harvey's New Eyes | Daedalic Entertainment | 2011 | Windows | adventure | | | label | |
| Edna Breaks Out | Daedalic Entertainment | 2008 | Linux | adventure Humorous | | | label | |
| Edna Breaks Out | Daedalic Entertainment | 2008 | Windows | adventure Humorous | | | label | |
| Egypt II: The Heliopolis Prophecy | Cryo Interactive | 2001 | PS | adventure edutainment | image | | label | |
| Egypt II: The Heliopolis Prophecy | Cryo Interactive | 2000 | Windows | adventure puzzle Historical | image | | label | |
| Eien no Filena | Tokuma Shoten | 1995 | SNES | role-play Fantasy | image | | label | |
| EITR | Eneme Entertainment | 2016 | Linux | action/reflex role-play | | | label | |
| El Mago de Oz | Idealogic | 1985 | MSX2 | adventure Fantasy | image | | label | |
| El Viento | Wolf Team | 1991 | Mega Drive | action/reflex platformer Manga | image | subject | label | |
| Eldritch | Minor Key Games | 2013 | Linux | action/reflex Fantasy | | | label | |
| Eldritch: Mountains of Madness | Minor Key Games | 2014 | Linux | action/reflex Fantasy | | | label | |
| ElePaperAction | EGS | 2005 | Windows | beat 'em up platformer shooter Manga | image | | label | |
| Ellaria: Cotton & Cream | Fablesoft Studios | 2016 | Linux | role-play Fantasy | | | label | |
| Elvira: The Arcade Game | MicroValue | 1991 | Amiga | platformer shooter adventure | image | | label | |
| Emily the Strange: Strangerous | Exozet Games | 2011 | Nintendo DS | adventure puzzle | image | | label | |
| Eminence: Xander's Tales | Aeterna Studios | 2014 | Windows | casino/cards role-play | | | label | |
| Emma at the Farm | White Birds Productions | 2007 | Nintendo DS | action/reflex edutainment | image | | label | |
| Emma in the Mountains | White Birds Productions | 2008 | Nintendo DS | action/reflex edutainment | image | | label | |
| Empty Horizons | ebi-hime | 2016 | Linux | simulation adventure Manga | | | label | |
| Enclave | TopWare Interactive | 2016 | Linux | role-play Fantasy | | | label | |
| Endgame | Cunning Developments | 2002 | PS2 | shooting gallery | image | subject | label | |
| Enemy Zero | Warp | 1998 | Windows | action/reflex adventure Horror | image | subject | label | |
| Enemy Zero | Warp | 1996 | Saturn | action/reflex adventure Horror | image | | label | |
| Energy Hook | Happion Laboratories | TBA | Linux | simulation sport Science Fiction | | | label | |
| Engage To Zeldawock | author | 2012 | Linux | shooter Fantasy | image | subject | label | |
| Enigmatis: The Ghosts of Maple Creek | Artifex Mundi | 2015 | Linux | adventure | | | label | |
| Entanglement | POLIMI Game Collective | 2017 | Linux | | | | label | |
| Entity | Loriciel | 1993 | Amiga | beat 'em up platformer | image | | label | |
| Entity | Loriciel | 1993 | MS-DOS | beat 'em up platformer | | | label | |
| Epistory - Typing Chronicles | Fishing Cactus | 2016 | Windows | action/reflex Cartoon | image | | label | |
| Ero Eater | るしまる堂 | 2013 | Windows | action/reflex Manga | image | | label | |
| Eryi's Action | Xtal Sword | 2011 | Windows | platformer Cartoon | image | | label | |
| Eryi's Action | Xtal Sword | 2011 | Linux | platformer Cartoon | | | label | |
| Eschalon: Book II | Basilisk Games | 2010 | Linux | role-play turn-based Fantasy | image | | label | |
| Eternal Darkness : Sanity's Requiem | Silicon Knights | 2002 | GameCube | action/reflex adventure Fantasy | image | subject | label | |
| Eternal Daughter | Blackeye Software | 2002 | Windows | action/reflex platformer Fantasy | image | subject | label | |
| Eternal Fighter Zero | Twilight Frontier | 2001 | Windows | fighting Manga | image | | label | |
| Eternal Light | Revistronic | 2008 | Windows | action/reflex adventure Fantasy | image | subject | label | |
| Eternal Light | Revistronic | 2008 | X360 | action/reflex adventure Fantasy | image | | label | |
| Eternal Light | Revistronic | 2008 | PS3 | action/reflex adventure Fantasy | image | | label | |
| EVE Online | CCP Games | 2007 | Linux | simulation role-play Science Fiction | | | label | |
| Evergirl | Artificial Mind & Movement | 2005 | GBA | adventure | image | subject | label | |
| Ex-Mutants | Sega | 1992 | Mega Drive | platformer shooter Science Fiction | image | | label | |
| Excalibur 2555 AD | Telstar | 1997 | Windows | maze role-play Fantasy | image | | label | |
| Excave III: Tower of Destiny | Mechanic Arms | 2015 | 3DS | action/reflex role-play Manga | image | subject | label | |
| eXperience112 | Lexis Numérique | 2007 | Windows | adventure puzzle | image | subject | label | |
| Experiment Pleasure | Sore Hand Games | 2010 | Linux | simulation Erotic | image | | label | |
| Eye of the Beholder | Westwood Associates | 1991 | Amiga | role-play Fantasy | image | | label | |
| Eye of the Beholder | NuFX | 1993 | Lynx | role-play Fantasy | image | | label | |
| Eye of the Beholder | Westwood Studios | 1991 | MS-DOS | role-play Fantasy | image | | label | |
| Eye of the Beholder | author | 2006 | Amiga AGA | role-play Fantasy | image | | label | |
| Eye of the Beholder | ? | 2022 | C64 | role-play Fantasy | | | label | |
| Eye of the Beholder | ? | 2022 | C128 | role-play Fantasy | | | label | |
| Eye of the Beholder | Pony Canyon | 1992 | NEC PC9801 | role-play Fantasy | image | | label | |
| Eye of the Beholder | Capcom Entertainment | 1994 | SNES | action/reflex role-play Fantasy | image | | label | |
| Eye of the Beholder | FCI;Pony Canyon | 1994 | Mega-CD | action/reflex role-play Fantasy | image | subject | label | |
| Eye of the Beholder II: The Legend of Darkmoon | Westwood Studios | 1992 | Amiga | action/reflex role-play Fantasy | image | subject | label | |
| Eye of the Beholder II: The Legend of Darkmoon | Westwood Associates | 1991 | MS-DOS | action/reflex role-play Fantasy | image | | label | |
| Eye of the Beholder II: The Legend of Darkmoon | Westwood Associates | 2015 | Linux | action/reflex role-play Fantasy | | | label | |
| Eye of the Beholder III: Assault on Myth Drannor | SSI | 1993 | MS-DOS | action/reflex role-play Fantasy | image | | label | |
| Eye of the Beholder III: Assault on Myth Drannor | SSI | 2015 | Linux | action/reflex role-play Fantasy | | | label | |
