| title | developer | year | platform | | pop. |
|---|
| AI War: Fleet Command | Arcen Games | 2009 | Windows | strategy Science Fiction | image | | label | |
| AI War: Fleet Command | Arcen Games | 2014 | Linux | strategy Science Fiction | | | label | |
| Ascendancy | The Logic Factory | 1995 | MS-DOS | strategy turn-based Science Fiction | image | | label | |
| Ascendancy | The Logic Factory | 2011 | iOS | strategy turn-based Science Fiction | | | label | |
| Battlestation: Harbinger | Bugbyte | 2016 | Windows | simulation strategy Science Fiction | | | label | |
| Black Prophecy | Reakktor Media | 2011 | Windows | action/reflex shooter flight Science Fiction | image | subject | label | |
| Conquest: Frontier Wars | Fever Pitch Studios;Digital Anvil | 2001 | Windows | manag./econ. strategy Science Fiction | image | subject | label | |
| DarkStar One | Ascaron Entertainment | 2006 | Windows | shooter adventure Science Fiction | image | subject | label | |
| Darkstar One: Broken Alliance | Ascaron Entertainment | 2010 | X360 | shooter Science Fiction | image | | label | |
| Diaspora | ? | 2015 | BSD | action/reflex shooter simulation flight Science Fiction | | | label | |
| Diaspora: Shattered Armistice | Diaspora Development | 2012 | Linux | action/reflex shooter simulation flight Science Fiction | | | label | |
| Elite | Revelation Software | 1996 | SAM | simulation flight | | | label | |
| Endless Sky | author | 2015 | Linux | shooter simulation flight Science Fiction | | | label | |
| Endless Sky | author | 2015 | Windows | shooter simulation flight Science Fiction | | subject | label | |
| EVE Online | CCP Games | 2003 | Windows | simulation role-play Science Fiction | image | | label | |
| EVERSPACE | ROCKFISH Games | 2017 | Windows | shooter Science Fiction | image | | label | |
| EVERSPACE | ROCKFISH Games | 2017 | Xbox One | shooter Science Fiction | | | label | |
| Evochron Alliance | StarWraith 3D Games | 2005 | Windows | shooter simulation flight Science Fiction | | | label | |
| Evochron Legends | StarWraith 3D Games | 2009 | Windows | shooter simulation flight Science Fiction | image | | label | |
| Evochron Renegades | StarWraith 3D Games | 2007 | Windows | shooter simulation flight Science Fiction | image | | label | |
| Fractured Space | Edge Case Games | 2016 | Windows | action/reflex Science Fiction | image | subject | label | |
| Free Stars: The Ur-Quan Masters | Pistol Shrimp | 2024 | Windows | shooter strategy Science Fiction | | subject | label | |
| Freelancer | Digital Anvil | 2003 | Windows | action/reflex shooter flight Science Fiction | image | subject | label | |
| Freelancer | author | 2016 | Linux | action/reflex shooter flight Science Fiction | | | label | |
| Frontier: Elite II | Gametek | 1993 | MS-DOS | simulation flight manag./econ. Science Fiction | image | | label | |
| FTL: Faster Than Light | Subset Games | 2012 | Linux | simulation role-play Science Fiction | | | label | |
| FTL: Faster Than Light | Subset Games | 2012 | Windows | simulation strategy role-play Science Fiction | image | | label | |
| FTL: Faster Than Light | Subset Games | 2012 | Mac OS X | simulation strategy role-play Science Fiction | | | label | |
| FTL: Faster Than Light | Subset Games | 2014 | iOS | simulation strategy role-play Science Fiction | | | label | |
| Genesis Rising | Metamorf Studios | 2007 | Windows | strategy Science Fiction | image | subject | label | |
| Into the Fire | Yosemite Entertainment | 1999 | Windows | shooter Science Fiction | image | subject | label | |
| Master of Orion | MicroProse | 1990 | Mac OS Classic | manag./econ. strategy turn-based Science Fiction | image | | label | |
| Master of Orion III | Quicksilver Software | 2003 | Windows | manag./econ. strategy turn-based Science Fiction | image | subject | label | |
| Master of Orion III | Quicksilver Software;MacSoft | 2003 | Mac OS Classic | manag./econ. strategy turn-based Science Fiction | image | | label | |
| Master of Orion III | Quicksilver Software;MacSoft | 2003 | Mac OS X | manag./econ. strategy turn-based Science Fiction | | | label | |
| miniElite | Omiod | 2013 | Internet Only | adventure turn-based Science Fiction | image | | label | |
| Nexus – The Jupiter Incident | Mithis Entertainment | 2004 | Windows | strategy Science Fiction | image | subject | label | |
| Omnicron Conspiracy | First Star Software | 1989 | MS-DOS | adventure Science Fiction | image | | label | |
| Omnicron Conspiracy | First Star Software | 1990 | Atari ST | adventure Science Fiction | image | | label | |
| Omnicron Conspiracy | First Star Software | 1990 | Amiga | adventure Science Fiction | image | | label | |
| Oolite | aegidian.org;Creative Commons | 2006 | Linux | shooter simulation flight Science Fiction | image | subject | label | |
| Oolite | aegidian.org;Creative Commons | 2006 | Unix | shooter simulation flight Science Fiction | | | label | |
| Oolite | ? | ? | Pandora | shooter simulation flight Science Fiction | | | label | |
| Orion | author | 1988 | Mac OS Classic | simulation Science Fiction | | subject | label | |
| Pioneer | author | 2011 | Linux | simulation flight | | | label | |
| Rebel Galaxy | Double Damage Games | 2015 | Windows | action/reflex Science Fiction | image | | label | |
| Sins of a Solar Empire | Ironclad Games | 2008 | Windows | manag./econ. strategy Science Fiction | image | subject | label | |
| Sins of a Solar Empire: Entrenchment | Ironclad Games | 2009 | Windows | simulation manag./econ. strategy Science Fiction | image | | label | |
| Solar Winds II: Universe | Stone Interactive Media | 1992 | MS-DOS | action/reflex adventure Science Fiction | image | | label | |
| Spore | Maxis | 2008 | Windows | action/reflex simulation manag./econ. strategy Science Fiction | image | subject | label | |
| Star Control | Toys for Bob | 1990 | MS-DOS | action/reflex strategy Science Fiction | image | | label | |
| Star Control | Toys for Bob | 1990 | Amiga | action/reflex strategy Science Fiction | image | | label | |
| Star Control | Toys for Bob | 2012 | Mac OS X | action/reflex strategy Science Fiction | | | label | |
| Star Control 2 | Toys For Bob | 2012 | Mac OS X | action/reflex shooter adventure role-play Science Fiction | | | label | |
| Star Control 2: Time Warp | ? | 2001 | BeOS | shooter strategy Science Fiction | | | label | |
| Star Control 3 | Legend Entertainment | 2012 | Mac OS X | action/reflex shooter manag./econ. strategy adventure Science Fiction | | | label | |
| Star Control 3 | Legend Entertainment | 1996 | MS-DOS | action/reflex shooter manag./econ. strategy adventure Science Fiction | image | | label | |
| Star Control II | Toys For Bob | 1992 | MS-DOS | action/reflex shooter adventure role-play Science Fiction | image | | label | |
| Star Control II | Toys For Bob | 1993 | 3DO | action/reflex shooter adventure Science Fiction | image | | label | |
| Star Control II: The Ur-Quan Masters | Toys for Bob | 2002 | Linux | shooter strategy Science Fiction | | | label | |
| Star Shipping | Corbomite Games | 2012 | Linux | manag./econ. Science Fiction | | | label | |
| Star Trader | author | 1974 | DEC PDP-1 | simulation manag./econ. Science Fiction | image | subject | label | |
| Star Trader | Computerware | 1984 | Tandy Coco | simulation flight manag./econ. shooting gallery Science Fiction | | | label | |
| Star Trader | Compucolor Corporation | 1980 | Compucolor II | simulation manag./econ. Science Fiction | | | label | |
| Star Trek | Washington Apple Pi | 198? | Apple III | edutainment rhythm puzzle Science Fiction | | | label | |
| Star Trek Online | Cryptic Studios;Perpetual Entertainment | 2010 | Windows | action/reflex role-play Science Fiction | image | subject | label | |
| Star Trek: Conquest | 4J studios | 2007 | Wii | action/reflex strategy Science Fiction | image | subject | label | |
| Star Trek: Conquest | 4J studios | 2007 | PS2 | action/reflex strategy Science Fiction | image | | label | |
| Star Trek: Legacy | Mad Doc Software | 2006 | X360 | action/reflex strategy Science Fiction | image | subject | label | |
| Star Trek: Legacy | Mad Doc Software | 2006 | Windows | action/reflex strategy Science Fiction | image | subject | label | |
| Starpoint Gemini 2 | Little Green Man Games | 2014 | Windows | action/reflex role-play Science Fiction | image | | label | |
| Starscape | Moonpod | 2003 | Windows | shooter adventure turn-based Science Fiction | image | subject | label | |
| Starsector | Fractal Softworks | 2013 | Windows | simulation strategy role-play Science Fiction | image | subject | label | |
| Strange Adventures in Infinite Space | Digital Eel | 2002 | Windows | strategy adventure Science Fiction | | | label | |
| Strange Adventures in Infinite Space | Digital Eel | 2002 | Mac OS X | strategy adventure Science Fiction | | | label | |
| Strange Adventures in Infinite Space | Digital Eel | ? | Palm | strategy adventure Science Fiction | | | label | |
| Strange Adventures in Infinite Space | Digital Eel | ? | WinCE | strategy adventure Science Fiction | | | label | |
| Strange Adventures in Infinite Space | Digital Eel | ? | Linux | strategy adventure Science Fiction | | | label | |
| Strike Suit Zero | Born Ready Games | 2013 | Windows | shooter Science Fiction | image | subject | label | |
| Super Star Trek | Washington Apple Pi | 198? | Apple III | edutainment rhythm puzzle Science Fiction | | | label | |
| The Adventures of Rad Gravity | Interplay | 1990 | NES | platformer Science Fiction | image | subject | label | |
| The Babylon Project | The Babylon Project | ? | Linux | shooter Science Fiction | image | | label | |
| The Long Journey Home | Daedalic Studio West | 2017 | Windows | action/reflex adventure Science Fiction | | | label | |
| The Long Journey Home | Daedalic Studio West | 2017 | PS4 | action/reflex adventure Science Fiction | | | label | |
| The Long Journey Home | Daedalic Studio West | 2017 | Xbox One | action/reflex adventure Science Fiction | | | label | |
| The Precursors | Deep Shadows | 2009 | Windows | simulation flight role-play Science Fiction | image | subject | label | |
| The Ur-Quan Masters | Toys for Bob | ? | Pandora | shooter strategy Science Fiction | | | label | |
| The Ur-Quan Masters | Toys for Bob | 2008 | GP2X | shooter strategy Science Fiction | | | label | |
| The Ur-Quan Masters | ? | 2011 | Windows | action/reflex manag./econ. adventure Humorous | image | subject | label | |
| The Ur-Quan Masters | Interstellar Frungy League;Toys For Bob | 2002 | Linux | action/reflex manag./econ. adventure Science Fiction | image | | label | |
| The Ur-Quan Masters | ? | 2002 | Mac OS X | action/reflex manag./econ. adventure Science Fiction | | | label | |
| The Ur-Quan Masters | ? | ? | GP2X | action/reflex Humorous | | | label | |
| The Ur-Quan Masters | ? | 2002 | BeOS | action/reflex manag./econ. adventure Science Fiction | | | label | |
| Transcendence | author | 2013 | Linux | action/reflex shooter role-play Science Fiction | | | label | |
| TW-Light | TimeWarp team | 2004 | Linux | shooter strategy Science Fiction | | | label | |
| X: Beyond the Frontier | Egosoft | 1999 | Windows | action/reflex simulation flight manag./econ. Science Fiction | image | subject | label | |
| X²: The Threat | Egosoft | 2003 | Windows | action/reflex simulation flight manag./econ. adventure Science Fiction | image | subject | label | |
| X²: The Threat | Egosoft;Linux Game Publishing | 2006 | Linux | action/reflex simulation flight manag./econ. Science Fiction | image | subject | label | |
| X²: The Threat | Egosoft | 2003 | Windows | action/reflex simulation flight manag./econ. Science Fiction | | | label | |
| X³: Farnham's Legacy | EGOSOFT | 2021 | Linux | action/reflex simulation flight manag./econ. adventure Science Fiction | | | label | |
| X³: Reunion | Egosoft | ? | Mac OS X | action/reflex simulation flight manag./econ. adventure Science Fiction | | | label | |
| X³: Reunion | Egosoft;Linux Game Publishing;Streamline Studios | 2008 | Linux | action/reflex simulation flight manag./econ. adventure Science Fiction | image | subject | label | |
| X³: Reunion | Egosoft | 2005 | Windows | action/reflex simulation flight manag./econ. adventure Science Fiction | image | | label | |
| X4: Foundations | Egosoft | 2019 | Linux | action/reflex simulation flight manag./econ. adventure Science Fiction | | | label | |
