| title | developer | year | platform | | pop. |
|---|
| E.T. | Sinclair User | 1983 | ZX Spectrum | action/reflex | | | label | |
| E.T. the Extra-Terrestrial | Atari | 1982 | Atari 2600 | action/reflex | image | subject | label | |
| Ebony Spire: Heresy | Bearded Giant Games | 2017 | Linux | | | | label | |
| El Mundo Perdido | Topo Soft | 1988 | MSX | platformer adventure Science Fiction | image | | label | |
| Element4l | I-Illusions | 2014 | Linux | platformer Fantasy | | | label | |
| Elysian Shadows | Elysian Shadows Team | 2015 | Linux | action/reflex role-play Fantasy | | subject | label | |
| Enchanted Cave | Peterson Computer Services | 1982 | TRS-80 | adventure | | | label | |
| End of Time | author | 2010 | Linux | action/reflex adventure Fantasy | image | subject | label | |
| Energy | Quasar Soft | 1989 | PC Engine | platformer shooter Manga | image | | label | |
| Energy Hook | Happion Laboratories | TBA | Linux | simulation sport Science Fiction | | | label | |
| Entombed! | New Breed Software | 2003 | Linux | maze | image | subject | label | |
| Entombed! | New Breed Software;Begasus | 2003 | BeOS | maze | | | label | |
| Epilogue | Kraflab | 2012 | Linux | role-play | | | label | |
| Epiphany | author | ? | Linux | puzzle | image | subject | label | |
| Escape | May-Be Soft | 1996 | MS-DOS | adventure Manga | | | label | |
| Escape from Bug Island | Spike | 2006 | Wii | action/reflex adventure Horror | image | subject | label | |
| Escape from the Dungeon of the Gods | SoftSide | 1982 | TRS-80 | adventure Fantasy | image | | label | |
| Escape from the Dungeon of the Gods | SoftSide | 1982 | Atari 400/800 | adventure Fantasy | image | | label | |
| Escape from the Dungeon of the Gods | SoftSide | 1982 | Apple II E | adventure Fantasy | image | | label | |
| Eschalon: Book I | Basilisk Games | 2007 | Linux | role-play turn-based Fantasy | image | subject | label | |
| Eschalon: Book I | Basilisk Games | 2007 | Windows | role-play turn-based Fantasy | image | subject | label | |
| Eschalon: Book I | Basilisk Games | 2007 | Mac OS X | role-play turn-based Fantasy | image | subject | label | |
| Eschalon: Book II | Basilisk Games | 2010 | Windows | role-play turn-based Fantasy | image | | label | |
| Eschalon: Book II | Basilisk Games | 2010 | Mac OS X | role-play turn-based Fantasy | image | | label | |
| Eschalon: Book II | Basilisk Games | 2010 | Linux | role-play turn-based Fantasy | image | | label | |
| Explorer | 0judge0 | 2013 | Linux | role-play Fantasy | | | label | |
| Eye of the Beholder | Westwood Associates | 1991 | Amiga | role-play Fantasy | image | | label | |
| Eye of the Beholder | NuFX | 1993 | Lynx | role-play Fantasy | image | | label | |
| Eye of the Beholder | Westwood Studios | 1991 | MS-DOS | role-play Fantasy | image | | label | |
| Eye of the Beholder | author | 2006 | Amiga AGA | role-play Fantasy | image | | label | |
| Eye of the Beholder | ? | 2022 | C64 | role-play Fantasy | | | label | |
| Eye of the Beholder | ? | 2022 | C128 | role-play Fantasy | | | label | |
| Eye of the Beholder | Pony Canyon | 1992 | NEC PC9801 | role-play Fantasy | image | | label | |
| Eye of the Beholder | Capcom Entertainment | 1994 | SNES | action/reflex role-play Fantasy | image | | label | |
| Eye of the Beholder | FCI;Pony Canyon | 1994 | Mega-CD | action/reflex role-play Fantasy | image | subject | label | |
