| title | developer | year | game type | | pop. |
|---|
| ObsCure II | Hydravision | 2007 | Wii | action/reflex adventure Horror | image | | label | |
| Ocean Commander | Valcon Games;Lexicon Entertainment | 2009 | Wii | | | | | |
| Octomania | Compile Heart | 2008 | Wii | puzzle | image | | | |
| Offroad Extreme! Special Edition | Data Design Interactive | 2007 | Wii | | | | | |
| Offshore Tycoon | Valcon Games | 2009 | Wii | | image | | | |
| Ōkami | Clover Studio;Ready at Dawn | 2008 | Wii | action/reflex adventure Fantasy | image | | label | |
| Okiraku Air Hockey Wii | Arc System Works | 2008 | Wii | | | | | |
| Okiraku Daifugou Wii | Arc System Works | 2009 | Wii | | | | | |
| Okiraku Kart Wii | Arc System Works | 2009 | Wii | | | | | |
| Okiraku Ping Pong Wii | Arc System Works | 2008 | Wii | | image | | | |
| Okiraku Putter Golf Wii | Arc System Works | 2009 | Wii | | | | | |
| Okiraku Slot Car Racing Wii | Arc System Works | 2009 | Wii | | | | | |
| Okiraku Sugoroku Wii | Arc System Works | 2009 | Wii | | | | | |
| Okiraku Tennis Wii | Arc System Works | 2009 | Wii | | | | | |
| One Piece Unlimited Cruise Episode 1: Hidden Treasure in Tossing Wave | Ganbarion | 2008 | Wii | beat 'em up adventure Manga | image | | label | |
| One Piece Unlimited Cruise Episode 2: Awaken of Hero | Ganbarion | 2009 | Wii | beat 'em up adventure Manga | | | label | |
| One Piece: Unlimited Adventure | Ganbarion | 2007 | Wii | beat 'em up adventure Manga | image | | label | |
| Onechanbara: Bikini Zombie Slayers | Tamsoft | 2008 | Wii | action/reflex | image | | label | |
| Open Season | Ubisoft Montreal | 2006 | Wii | action/reflex | image | subject | label | |
| Opoona | ArtePiazza | 2007 | Wii | role-play | image | | | |
| Order Up! | SuperVillain Studios | 2008 | Wii | | image | | | |
| Osouji Sentai Clean Keeper | Lupinus | 2008 | Wii | adventure Manga | image | | label | |
| Our House: Party! | Budcat Creations | 2009 | Wii | | image | | | |
| Out of Galaxy: Gin no Corsica | Sunsoft | 2009 | Wii | | | | label | |
| Outdoor Action Double Pack | Mastiff | 2010 | Wii | | image | | | |
| Overlord: Dark Legend | Climax Studios | 2009 | Wii | action/reflex adventure Fantasy | image | | label | |
| Overturn | Studio Zan | 2008 | Wii | | image | | label | |
| Oyako de Asobo: Miffy no Omocha Bako | h.a.n.d. | 2010 | Wii | | | | | |
