| title | developer | year | game type | | pop. |
|---|
| E.I.: Exa Innova | Programmers-3 | 1984 | MSX | shooter Science Fiction | image | | label | |
| Eagle | Juliet Software | 1987 | MSX | shooter Science Fiction | image | | | |
| Echec | Loriciels | 1985 | MSX | board game | image | | label | |
| Eddie Kidd Jump Challenge | Martech | 1985 | MSX | action/reflex | image | | label | |
| Eddy 2 | HAL | ? | MSX | | | | | |
| Eggerland 2: Meikyuu Shinwa | HAL Laboratory | 1986 | MSX | maze puzzle Cartoon | image | | label | |
| Eggerland Mystery | HAL Laboratory | 1985 | MSX | maze puzzle Cartoon | image | | label | |
| El Capitán Trueno | Dinamic | 1989 | MSX | beat 'em up platformer Fantasy | image | | label | |
| El Cid | Dro Soft | 1987 | MSX | action/reflex Fantasy | image | | label | |
| El Mundo Perdido | Topo Soft | 1988 | MSX | platformer adventure Science Fiction | image | | label | |
| El Poder Oscuro | Zigurat | 1988 | MSX | action/reflex shooter Science Fiction | image | | label | |
| Eletron | author | 2006 | MSX | | | | | |
| Elevator Action | Nidecom Carry | 1985 | MSX | platformer shooter | image | | label | |
| Elidon | Orpheus | 1986 | MSX | action/reflex | image | subject | label | |
| Elite | Mr Micro | 1987 | MSX | simulation flight manag./econ. adventure Science Fiction | image | | label | |
| Emerald Isle | Level 9 Computing | 1985 | MSX | adventure | image | | label | |
| Emilio Butragueño 2 | Ocean | 1989 | MSX | sport | image | | label | |
| Emilio Butragueño Futbol | Topo Soft | 1988 | MSX | sport | image | | label | |
| Emilio Sanchez Vicario Grand Slam | Zigurat | 1989 | MSX | sport | image | | label | |
| En Ruta | Biosoft | 1985 | MSX | edutainment puzzle | image | | label | |
| Enchanted | Positive | 1989 | MSX | action/reflex | image | | label | |
| Erika | Jast | 1987 | MSX | adventure Manga | image | | | |
| Esvay | CD Systems | 1984 | MSX | | | | | |
| Ewoks and the Dandelion Warriors | author | 1987 | MSX | shooter Science Fiction | image | | label | |
| Exerion | Jaleco | 1984 | MSX | shooter Science Fiction | image | | label | |
| Exerion 2 Zorni | Jaleco | 1984 | MSX | | | | | |
| Exoide-Z | Casio Computer | 1986 | MSX | shooter Science Fiction | | | label | |
| Exploding Atoms | Sanyo | 1985 | MSX | | | | | |
| Exterminator | Eaglesoft | 1987 | MSX | | | | | |
| Eye | Endurance Games | 1988 | MSX | board game | image | | label | |
| F-1 Spirit: The Way to Formula-1 | Konami | 1987 | MSX | racing/driving | image | | label | |
| F-15 Strike Eagle | Novotrade | 1987 | MSX | simulation flight | image | | label | |
| F16 Fighting Falcon | Nexa Corporation | 1984 | MSX | simulation flight | image | | label | |
| Fa Tetris | FA Soft | 1989 | MSX | puzzle | | | | |
| Faeton | Jose Javier Franco Benitez | 2006 | MSX | | | | | |
| Fairy | ASCII | 1985 | MSX | | | | | |
| Fairy Land Story | Taito;Hot-B | 1987 | MSX | platformer | image | | | |
| Fantasm Soldier Valis | Wolf Team | 1986 | MSX | beat 'em up platformer Fantasy | image | | label | |
| Fantasy Zone | Pony Canyon | 1986 | MSX | shooter Cartoon | image | | label | |
| Farge | Melody Soft | 1988 | MSX | | | | | |
| Fathom | Interphase | 1985 | MSX | action/reflex | image | | label | |
| Feud | Binary Design | 1987 | MSX | action/reflex maze adventure Fantasy | image | | label | |
| Field Master | MSX GAMEBOOK | 1984 | MSX | | image | | label | |
| Final Countdown | Methodic Solutions | 1988 | MSX | simulation | image | | label | |
| Final Justice | Compile | 1985 | MSX | shooter | image | | | |
| Final Zone Wolf | Wolf Team | 1986 | MSX | shooter Manga | image | | label | |
| Finders Keepers | Mastertronic | 1986 | MSX | platformer adventure | image | | label | |
| Fire Rescue | Hudson Soft | 1984 | MSX | platformer | image | | label | |
| Fire Star | OMK Software | 1988 | MSX | | | | | |
| Fire Warrior | Electromagic | 1991 | MSX | | | | | |
| Firehawk | Players | 1987 | MSX | shooter Science Fiction | image | | label | |
| First Steps with the Mr. Men | PrImer Educational Software | 1985 | MSX | edutainment | image | | label | |
| Flappy | dB-SOFT | 1984 | MSX | puzzle | image | | label | |
| Flash Gordon | Icon Design | 1986 | MSX | action/reflex beat 'em up maze shooter Science Fiction | image | | label | |
| Flash Splash | Toshiba-EMI | 1984 | MSX | | | | | |
| Flicky | Micronet | 1986 | MSX | platformer | | | label | |
| Flight Deck | Aackosoft | 1986 | MSX | action/reflex flight strategy | image | | label | |
| Flight Deck II | Aackosoft | 1986 | MSX | action/reflex strategy | image | | label | |
| Flight Path 737 | Anirog | 1985 | MSX | simulation flight | image | | label | |
| Flight Simulator with Torpedo Attack | subLOGIC | 1988 | MSX | simulation flight Historical | image | | label | |
| Flipper Slipper | ASCII | 1984 | MSX | | | | | |
| Flop Chop | Sony | 1985 | MSX | | | | | |
| Flower! | Nihon Bussan | 1991 | MSX | board game Manga | | | | |
| Flying Witches | Ediciones Generales Anaya | 1985 | MSX | action/reflex | | | label | |
| Foot Volley | Players | 1986 | MSX | sport | image | | label | |
| Football | Nice Ideas | 1985 | MSX | sport | | | label | |
| Football Manager | Endurance Games;Addictive Games | 1987 | MSX | manag./econ. sport | image | | label | |
| Football Manager World Cup Edition | Addictive Games | 1990 | MSX | manag./econ. sport | image | | label | |
| Footballer of the Year | Gremlin Graphics | 1986 | MSX | action/reflex manag./econ. sport | image | | label | |
| Forbidden Fruit | Krypton Force | 1985 | MSX | action/reflex maze | image | | label | |
| Formation Z | Nippon Dexter;JALECO | 1985 | MSX | shooter | image | | label | |
| Formula 1 Simulator | Mastertronic | 1985 | MSX | racing/driving | image | | label | |
| Freddy Hardest | Dinamic | 1987 | MSX | beat 'em up platformer shooter Science Fiction | image | | label | |
| Freddy Hardest in South Manhattan | Iron Byte | 1989 | MSX | beat 'em up | image | | label | |
| Frogger | Konami | 1983 | MSX | action/reflex | image | | label | |
| Front Line | Taito | 1984 | MSX | shooter | image | | label | |
| Fruit Panic | Pony Canyon | 1984 | MSX | | | | | |
| Fruit Search | Takara | 1983 | MSX | puzzle | image | | label | |
| Fruity Frank | Kuma | 1984 | MSX | action/reflex | image | | label | |
| Funky Mouse | ZAP Corporation | 1984 | MSX | | | | | |
| Funky Punky | Genesis Soft | 1987 | MSX | platformer | image | | label | |
| Future Knight | Gremlin Graphics | 1986 | MSX | platformer Science Fiction | image | | label | |
| FX-15 | Mind Games Espana | 1987 | MSX | | | | | |
